A horrible new cancer is destroying the United States, almost without anybody noticing. Pentagocarcinoma (PCa) is probably not a new disease, but began about the time of World War 2. Unfortunately, it is now completely out of control, evading all attempts at treatment.
Like most epithelial cancers, PCa began on the periphery (of Washington, in Virginia in fact) but relentlessly enlarged itself, like all cancers, developing its own blood supply to the cost of its host. Then it metastasized.
The metastases are global, and themselves expand, making their own blood supplies, while the host withers. Treatment at this stage would be restricted to only the most drastic chemotherapy. The prognosis is poor, even absent rigid denial of the diagnosis.